Dover sole (Solea solea L.) has become a promising species in aquaculture. It has a high market value and moreover a reliable sole production would reduce fishing pressure on wild Dover sole populations. Unfortunately, due to outbreaks of infectious diseases, the survival in marine larviculture is low and unpredictable. Vibriosis is one of the most challenging bacterial diseases to tackle in the early life stages. It is caused by bacteria belonging to the genus Vibrio, with Vibrio anguillarum being the most prominent member. We should try and avoid the use of antimicrobial agents or chemical additives to prevent and control infectious diseases due to the emerging antimicrobial resistance, the potential transfer of antimicrobial resistance genes to fish or human pathogens and the possibility that antimicrobials can enter the human food chain. To be able to develop alternative treatments to prevent and combat this disease, it is imperative to better understand the pathogenesis of vibriosis. To achieve this, there is a great need for reliable and reproducible experimental infection models.
Ghent University developed the first experimental challenge model for vibriosis in Dover sole larvae. In addition, they also evaluated the protective potential of probiotic candidates for Dover sole in vitro and subsequently in vivo by means of the pinpointed challenge model. If you would like to know more about this study, please read the full article: https://www.researchgate.net/publication/323408648_Experimental_infection_model_for_vibriosis_in_Dover_sole_Solea_solea_larvae_as_an_aid_in_studying_its_pathogenesis_and_alternative_treatments.
Reference: De Swaef, E., Vercauteren, M., Duchateau, L., Haesebrouck, F. & Decostere, A. (2018). Experimental infection model for vibriosis in Dover sole (Solea Solea) larvae as an aid in studying its pathogenesis and alternative treatments. Veterinary research 49:24.